Selected discoveries from the Feringa group laboratories


Auto-Amplification of Molecular Chirality
Angew.Chem., DOI: 10.1002/anie.201311160


Optical control of antibacterial activity
Nature Chem., DOI: 10.1038/nchem.1750

Directed Cross-coupling of Organolithium Compounds
Nature Chem., DOI: 10.1038/nchem.1678

Palladium Catalyzed Selective Anti-Markovnikov Oxidation of Allylic Esters
Angew. Chem., DOI: 10.1002/anie201301809


Ultrafast Dynamics in the Power Stroke of a Molecular Rotary Motor
Nature Chem. 4, 547 - 551

Azobenzene photoswitches for Staudinger-Bertozzi Ligation
Angew. Chem. 52,2068-2072

Visible Light Driven Molecular Motor
J. Am. Chem. Soc. 134, 17613-9


Electrically driven directional motion of a four-wheeled molecule on a metal surface
Nature, 479, 208-211

Reversing the direction in a light-driven molecular motor
Nature Chem. 3, 53-60

Dynamic Control of Chiral Space in a Catalytic Asymmetric Reaction using a Molecular Motor
Science, 331, 1429-1432

Light-induced disassembly of self-assembled vesicle-capped nanotubes observed in real-time
Nanotech. 6, 547-552

Catalytic Asymmetric Carbon-Carbon Bond Formation via Allylic Alkylations with Organolithium Compounds
Nature Chem. 3, 377-381


Copper-Catalyzed Enantioselective Synthesis of trans-1-alkyl-2-substituted cyclopropanes via Tandem conjugate addition intramolecular enolate trapping
J. Am. Chem. Soc. 132, 14349-14351

Spontaneous generation and patterning of polymeric surface toroids
Chemical Science, 1, 469-472

Photoswitchable Intramolecular H-stacking of Perylenebisimide
J. Am. Chem. Soc. 132, 4191-4196

Light induced control of the Protein trans location by SecY lateral gate
Angew. Chem. 49, 7234-7238

Catalytic enantioselective syn-hydration of enones in water using a DNA-based catalyst
Nature Chem. 2, 991-995


Aldehyde Selective Wacker Oxidations of Phthalimide Protected Allylic Amines: A New Catalytic Route to β3-Amino Acids
J.Am.Chem.Soc. 131, 9473-9474

Enantioselective Friedel-Crafts Reactions in Water Using a DNA-Based Catalyst
Angew. Chem. 48, 3346-3348

Intermolecular Repulsion through Interfacial Attraction: Toward Engineering of Polymorphs
J.Am.Chem.Soc. 131, 15655-15659

Iridium/Monodentate Phosphoramidite Catalyzed Asymmetric Hydrogenation of N-Aryl Imines
J.Am.Chem.Soc. 131, 8358-8359

Optimizing rotary processes in synthetic molecular motors
PNAS, 106, 6919-16924


Autonomous propulsion of carbon nanotubes powered by a multienzyme ensemble
Chem. Commun. 1533-1535

Reversible conductance switching in molecular devices
Adv. Mater. 20, 1467-1468

On/off photoswitching of the electropolymerizability of terthiophenes
J. Am. Chem. Soc. 130,12850-12851

Dynamic kinetic resolution of racemic beta-haloalcohols: Direct access to enantioenriched epoxides
J. Am. Chem. Soc. 130, 13508-13509

MHz unidirectional rotation of molecular rotary motors
J. Am. Chem. Soc. 130,10484-5

Biologically active Phytophthora mating hormone prepared by catalytic asymmetric total synthesis
PNAS 105: 8507-8512


Molecular transmission: controlling the twist sense of a helical polymer with a single light-driven molecular motor
Angew. Chem. 46, 3693-3696

An astrophysically-relevant mechanism for amino acid enantiomer enrichment
Chem. Comm. 2578-2580

DNA-Based Catalytic Enantioselective Michael Reactions in Water
Angew. Chem. 46, 9308-9311

Controlled rotary motion in a monolayer of molecular motors
Angew. Chem. 46, 1278-1280


Rotation of a microscopic object by a light-driven molecular motor
Nature, 440, 7081,163

Rationally designed chemical modulators convert a bacterial channel protein into a pH-sensory valve
Angew. Chem. 45, 3126-3130

Reversible conductance switching of single diarylethenes on a gold surface
Adv. Mater, 18, 1397

Total synthesis of enantiopure beta-D-mannosyl phosphomycoketides from Mycobacterium tuberculosis
J. Am. Chem. Soc. 128, 4546-4547

Copper catalyzed asymmetric synthesis of chiral allylic esters
J. Am. Chem. Soc. 128, 15572-15573

A ligand-library approach to the highly efficient rhodium/phosphoramidite-catalyzed asymmetric arylation of N,N-dimethyl-sulfamoyl-protected aldimines
Angew. Chem. 45, 2789-2791


Unidirectional Molecular Motor on a Gold Surface
Nature, 2005, 437,1337-1340

A Reversible Unidirectional Rotary Motor driven by Chemical Energy
Science, 310, 80-82

A Light-Actuated Nanovalve Derived from a Channel Protein
Science, 309, 755-758

An Iterative Catalytic Route to Enantiopure Deoxypropionate Subunits: Asymmetric Conjugate Addition of Grignard Reagents to α,β-Unsaturated Thioesters
J. Am. Chem. Soc. 127, 9966-9967

Macroscopic expression of the chirality of aminoalcohols by a double amplification mechanism in liquid crystalline media
J. Am. Chem. Soc. 127, 13480-13481

Dynamic Chiral Selection and Amplification using Photoresponsive Organogelators
J. Am. Chem. Soc. 127, 13804-13805

DNA-based Asymmetric Catalysis
Angew. Chem. 44, 3230-3232

Light-Driven Dynamic Pattern Formation
Angew. Chem. 44, 2373-2376

Achiral ligands dramatically enhance rate and enantioselectivity in the Rh/Phosphoramidite-catalyzed hydrogenation of α,β-disubstituted unsaturated acids
Angew. Chem. 44, 4209-4212